Computational Biology Seminar
The Computational Biology Seminar is a weekly series of seminars on topics in computational biology presented by invited speakers, Duke faculty and CBB doctoral and certificate graduate students.
Spring 2010 Schedule
Time: 11am - noon
Place: 4233 French
| Date | Speaker | Institution | Title of Presentation |
| 1/4 | N/A | No Seminar | No Seminar |
| 1/11 | N/A | No Seminar | No Seminar |
| 1/18 | N/A | No Seminar | Martin Luther King Holiday |
| 1/25 | N/A | No Seminar | No seminar due to Jan 27th joint presentation with Systems Biology by Walter Fontana of Harvard |
| 2/1 | Noah Rosenberg | University Michigan | Worldwide Human genetic variation = implications for disease association studies in diverse populations |
| 2/8 | Kevin Wiehe Tom Kepler Post doc | Duke University | Molecular simulations of HIV gp41 peptides |
| 2/15 | Andrew Allen, PhD | Biostatistics & Bioinformatics Duke University | "Using haplotype sharing to map disease genes" |
| 2/22 | Carlos Bustamante | Cornell | "Population Genetics in the Personal Genome Era" |
| 3/1 | Nicky Lekprasert, CBB PhD student | Uwe Ohler Group | Thermodynamics properties of micro RNA-mRNA duplex formation for micro RNA target prediction |
| 3/8 | N/A | No Seminar | Spring Break |
| 3/15 | Gil Bejerano | Stanford | Comparative and Functional Genomics of the Evolution of Human-Specific Traits |
| 3/22 | Kyle Roberts, CBB PhD student |
Bruce Donald Group | |
| 3/29 | Hsiang-Yu Yuan, CBB PhD student | Katia Koelle Group | |
| 4/5 | |||
| 4/12 | Weizi Huang, CBB PhD Student |
Ed Iverson Group | |
| 4/19 | Orly Alter | University of Texas at Austin | Discovery of Mechanisms from Mathematical Modeling of DNA Microarray |
| 4/26 | Greg Voth | Utah | Systematic Multiscale Simulation of Biomolecular Assemblies |
| 5/3 | N/A | No Seminar | No seminar due to April 30th joint presentation with Statistics by Ingo Ruczinski |
Fall 2009 Schedule
Time: 11am - noon
Place: 4233 French
| Date | Speaker | Institution | Title of Presentation |
| 9/9* | Megan Owen | North Carolina State University Dept. of Mathematics | A Fast Algorithm for Computing Geodesic Distances in Tree |
| Please note that 9/9 presentation will be held on Wednesday at 4pm in 4233 French. | |||
| 9/14 | Patrick Charbonneau | Duke University Dept. of Chemistry | Nonspecific Protein-Protein Interactions and Crystallization |
| 9/21 | Xin Guo | CBB Certificate Student, Alex Hartemink Group | Branching Process Deconvolution Algorithm Reveals a Detailed Cell Cycle Transcriptional Program |
| 9/28 | Melissa Fazzari | Albert Einstein College of Medicine Dept. of Epidemiology & Population Health, Dept. of Genetics | Statistical issues in the design and analysis of epigenome-wide association studies |
| 10/5 | Fall Break - No Seminar | ||
| 10/12 | Nicole Johnson | CBB PhD Student, Lindsay Cowell Group | The Identification of Genes Associated with Host Susceptibility to Staphlycoccus aureus Infection |
| 10/19 | Rui Wang | CBB PhD Student, Erich Jarvis Group | On the origin of vocal learning: correlated mutations among the three purported mammalian vocal learners |
| 10/26 | Xianrui Cheng | CBB PhD Student, Josh Socolar and Dave McClay Groups | An autonomous Boolean model for the sea urchin endomesoderm specification |
| 11/2 | Hilmar Lapp | National Evolutionary Synthesis Center (NESCent) | Cyberinfrastructure and bioinformatics to enable evolutionary synthesis: Some highlights from NESCent |
| 11/9 | Todd Wasson | CBB PhD Student, Alex Hartemink Group | An Ensemble Model of Competitive Multi-factor Binding of the Genome |
| 11/16 | Ahmad Hariri | Duke University Dept. of Psychology and Neuroscience | Biological Pathways to Psychopathology |
| 11/23 | Parawee Lekprasert | CBB PhD Student, Uwe Ohler Group | Thermodynamics properties of microRNA-mRNA duplex formations for microRNA target predictions |
| 11/30 | Sheng Feng | Duke University Dept. of Biostatistics & Bioinformatics | Omics data analysis: small sample size and false positives |
| 12/7 | Svati Shah | Duke University Dept. of Cardiology | Genomic and Metabolomic Phenotypes of Complex Cardiovascular Disease |
Spring 2009 Schedule
Time: 4:00 - 5:00pm
Place: 4233 French
| Date | Speaker | Institution | Title of Presentation |
| 1/14 | Matt Eaton | CBB PhD Student, David MacAlpine and Terry Furey Groups | The Role of Nucleosome Positioning in Replication Origin Selection |
| 1/21 | Sandeep Dave | Dept. of Medicine | High Throughput Biology to Improve the Diagnosis and Prognosis of B cell malignancies |
| 1/28 | Joe Lucas | IGSP | Alternative Strategies for Analyzing High Dimensional Data |
| 2/4 | Katie Pollard | Gladstone Institutes, University of California San Francisco | Accelerated evolution in the human genome |
| 2/11 | No Seminar | ||
| 2/18 | Andreas Pfenning | CBB PhD Student, Erich Jarvis and Alex Hartemink Groups | Singing in the Brain: The gene expression of song production |
| 2/25 | Blanche Capel | Dept. of Biology | Sex and the Circuitry |
| 3/4 | Ian Holmes | Dept. of Bioengineering, UC Berkeley | Bayesian reconstruction of insertion-deletion histories in genes and genomes |
| 3/11 | No Seminar | ||
| 3/17* | Samuel Levy | J Craig Venter Institute | Comprehensive variant detection in human individuals and populations |
| 3/25 | Chris Bailey-Kellogg | Dept. of Computer Science, Dartmouth College | Probabilistic Graphical Models of Residue Constraints in Proteins and Protein Complexes |
| 4/1 | Nicolas Buchler | Rockefeller University | Bait and switch: How protein sequestration generates a flexible ultrasensitive response |
| 4/8 | Ryan Baugh | Dept. of Biology | RNA Polymerase II Accumulates on Promoters of Growth and Development Genes During Developmental Arrest in C. elegans |
| 4/15 | David McClay | Dept. of Biology | Connecting gene regulatory network states in a dynamic system |
| 4/22 | Ana Sales | CBB PhD Student, Tom Kepler Group | Clustering of Dendritic Cell Temporal Gene Expression Data with a Dirichlet and Gaussian Processes Mixture Model |
| 4/29 | Elizabeth Rach | CBB PhD Student, Uwe Ohler Group | Prevalence, Condition-Specificity, and Core Promoter Dynamics of Alternative Transcription Start Sites in the Drosophila Genome |
*Please note that the seminar the week of March 16th will be on Tuesday, March 17th.
Fall 2008 Schedule
Time: 4:00 - 5:00pm
Place: 103 Bryan Research Building
| Date | Speaker | Institution | Title of Presentation |
| 9/3 | Curtis Layton | CBB PhD Student, Homme Hellinga Group | Computational design of protein-protein interactions |
| 9/10 | Ed Ionides | University of Michigan Dept. of Statistics | Infectious disease dynamics: a statistical perspective |
| 9/17 | Saurabh Sinha | University of Illinois at Urbana-Champaign | Comparative genomics of regulatory sequences in medium to large divergence regimes |
| 9/24 | Supriya Munshaw | CBB PhD Student, Tom Kepler Group | A large-scale analysis of the antibody response against HIV-1 in acute and chronic individuals |
| 10/1 | Karen Mohlke | University of North Carolina Chapel Hill Dept. of Genetics | Common genetic variants for metabolic and cardiovascular traits |
| 10/8 | Eric Stone | North Carolina State University Dept. of Statistics | Objective clustering for inference in systems genetics |
| 10/15 | Cliburn Chan | Dept. of Biostatistics & Bioinformatics | Statistical modeling of multi-parameter flow cytometry |
| 10/22 | Ken Yokoyama | CBB PhD Student, Greg Wray and Uwe Ohler Groups | Functional sequence predictions using position-specific overrepresentation and inter-motif distance preferences |
| 10/29 | Fred Nijhout | Department of Biology | Robustness and Homeostasis in a Complex Network: The Details Really Matter |
| 11/5 | Bei Wang | CBB Certificate Student, Herbert Edelsbrunner Group | Computing elevation maxima by searching the guass sphere |
| 11/12 | Anita Layton | Department of Mathematics | Multistable dynamics mediated by tubuloglomerular feedback in a model of coupled nephrons |
| 11/19 | Christina Leslie | Memorial Sloan-Kettering Institute Cancer Center | Deciphering microRNA-mediated regulation through perturbations in gene expression |
| 12/3 | Kiani Arkus, Michael Mayhew and Deborah Winter | Duke University Cell & Molecular Biology and Computational Biology & Bioinformatics Programs | De novo genomic sequencing of the fungus Holleya sinecauda by paired end Solexa sequencing |
| 12/10 | Mohamed Noor | Duke University | Effects of recombination on diversity and divergence between species in the Drosophila pseudoobscura species group |



