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The Duke Bioinformatics Shared Resource
(DBSR) collaborates with Cancer Center investigators on projects using genomic data, including transcriptome (microarray, SAGE) data, proteomic data, and sequence data. The goal of the DBSR is to consult and collaborate on the statistical design and analysis of cancer projects that include these and other types of genomic data, including linking these data to clinical data. Another goal is to provide or develop algorithms and computational tools for data manipulation, annotation, and comparison with public data. A further goal is to provide education for researchers and biostatisticians. The DBSR will continue to organize the annual Critical Assessment of Microarray Data Analysis (CAMDA) conference, and will work closely with Cancer Center Information Systems (CCIS) on the National Cancer Insistute (NCI) effort to construct a cancer based biomedical framework, Cancer Biomedical Informatics Grid (caBIG program). The interaction with other Cancer Center cores and the proposed cores is critical. We also propose a close interaction with the CALGB Statistical Center, located at Duke and directed by Dr. Stephen George. Technical support for hardware and software will be provided by CCIS.