IGSP Faculty

Geoffrey S. Ginsburg, MD, PhD

Geoffrey S. Ginsburg, MD, PhD

Director, Genomic Medicine, Duke Institute for Genome Sciences & Policy
Executive Director, Center for Personalized Medicine Duke Medicine
Professor of Medicine and Pathology Duke University Medical Center

Our mission is to develop and translate novel therapies and predictive biomarkers into clinical research and practice to optimize efficiency, effectiveness, and success in bringing the right therapy to the right patient at the right time.

Dr. Ginsburg is the founding director for Genomic Medicine at Duke and assumed his current position in the Duke Institute for Genome Sciences & Policy in 2004. He is also the founding executive director of the Center for Personalized Medicine established in the Duke University Health System in 2010.

While at Duke, Dr. Ginsburg has pioneered translational genomics, initiating programs in genome enabled biomarker discovery, longitudinal registries with linked molecular and clinical data, biomarker-informed clinical trials, and the development of novel practice models and implementation research for the integration of genomic tools in heath care systems. With a strong commitment to interdisciplinary science he has led projects to develop predictive models for common complex diseases using high dimensional genomic data as well as collaborations with engineering groups to develop novel point of care sensors. His work spans oncology, infectious diseases, cardiovascular disease and metabolic disorders, and his research is addressing the challenges for translating genomic information into medical practice using new and innovative paradigms, and the integration of personalized medicine into health care. He is an internationally recognized expert in genomics and personalized medicine with over 200 published papers, and funding from NIH, DOD, Air Force, DARPA, the Gates Foundation, and industry.

In 1990, he joined the faculty of Harvard Medical School, where he was director of Preventive Cardiology at Beth Israel Hospital and led a laboratory in applied genetics of cardiovascular disease at Children's Hospital. In 1997 he joined Millennium Pharmaceuticals Inc, as senior program director for cardiovascular diseases and was eventually appointed vice president of Molecular and Personalized Medicine, where he was responsible for developing pharmacogenomic strategies for therapeutics, as well as biomarkers for disease and their implementation in the drug development process.

He has received a number of awards for his research accomplishments, including the Innovator in Medicine Award from Millennium in 2004 and the Basic Research Achievement Award in Cardiovascular Medicine from Duke in 2005. He is a founding member and former board member of the Personalized Medicine Coalition, a senior consulting editor for The Journal of the American College of Cardiology, an editor for The HUGO Journal, and an editorial advisor for Science Translational Medicine. In addition he is the editor of Genomic and Personalized Medicine (Elsevier) whose first edition was published in 2009.

He has been a member of the Secretary of Veterans Affairs Advisory Council on Genomic Medicine and the National Advisory Council for Human Genome Research at NIH. He is currently an international expert panel member for Genome Canada, a member of the Board of External Experts for the National Heart, Lung and Blood Institute, the Institute of Medicine's Roundtable on Genome-Based Research to Human Health, and a member of the External Scientific Panel for the Pharmacogenomics Research Network. He has recently been appointed to the Advisory Council for the National Center for Advancing Translational Sciences at NIH and is the Vice Chair for the Cures Acceleration Network Board. He is also a member of the World Economics Forum's Global Agenda Council on Personalized and Precision Medicine.

He received his MD and PhD in biophysics from Boston University and completed an internal medicine residency at Beth Israel Hospital in Boston, MA. Subsequently, he pursued postdoctoral training in clinical cardiovascular medicine at Beth Israel Hospital and in molecular biology at Children's Hospital as a Bugher Foundation Fellow of the American Heart Association.

Learn more about Dr. Ginsburg's research in GenomeLIFE

Recent Publications