Projects & Collaborations
The broad focus of the group is on:
- Probabilistic models of high-dimensional (genomic) data;
- Geometry of high-dimensional (genomic) data;
- Topology of high-dimensional (genomic) data;
- Inference of mechanism in development of complex disease traits
Ongoing projects and collaborations (ordering invariant under the symmetric group). See our section on Research and Software for details.
- Jen-Tsan Chi, Phillip Febbo, Anil Potti, Duke:
Inference of mechanism in modeling cancer
(Elena Edelman, Justin Guinney, Stoyan Georgiev, Qiang Wu) - Terry Furey, Uwe Ohler, Duke:
Computational and statistical tools in molecular biology and genetics
(Elena Edelman, Justin Guinney, Stoyan Georgiev, Qiang Wu) - John Harer, Herbert Edelsbrunner, Duke:
Topology and probability
(Simon Lunagomez, Paul Bendich, Bei Wang) - Ding-Xuan Zhou, City University of Hong Kong, Mauro Maggioni, Duke:
Geometry and probabilistic models
(Kai Mao, Qiang Wu, Justin Guinney) - Feng Liang, UIUC, Mike West, Duke:
Bayesian non-parametrics
(Natesh Pillai, Kai Mao) - Robert Wolpert, Jonathan Mattingly, Duke:
Stochastic processes and stochastic differential equations
(Natesh Pillai, Qiang Wu)
Former members of the group:
- Karthik Jayasurya, CBB graduate rotation
- Todd Wasson, CBB graduate rotation
- Gunjan Verma, CBB graduate student in group
- Andreas Pfenning, CBB graduate rotation
- Matt Eaton, CBB graduate rotation
- Kuan-ming Lin, CS graduate rotation
- Ran Liu, CS graduate rotation, currently at Google
- Eric Alter, IGSP undergraduate summer fellow (Rutgers)
Funding:
We acknowledge the following funding sources who currently provide us with funding to undertake most of these projects:
- National Science Foundation: PI on DMS grant on probabilistic models and geometry for high-dimensional data.
- National Institute of General Medical Sciences (NIGMS): co-PI on the Duke National Center for Systems Biology (about 15 co-PIs)
- National Institutes of Health (NIH): co-PI on a grant on gene expression programs of lactic acidosis in human cancers (Jen-Tsan Chi PI).
- National Institutes of Health (NIH): co-PI on a grant on mTOR therapy in prostate cancer (Phillip Febbo PI).