Email: nm29 (at) duke.edu
Location: CIEMAS 2239
Systems Biology, Post-Transcriptional Gene Regulation
My primary interest is understanding the regulatory logic underlying post-transcriptional gene expression networks using a combination of biochemical and computational approaches. I completed my doctoral research at Duke in the UPGG in the lab of Jack Keene studying RNA-binding proteins.
University of California, San Diego
B.Sc. General Biology
Ph.D. Genetics and Genomics
Mukherjee N, Corcoran D, Nusbaum J, Reid D, Tuschl T, Ohler U, Keene JD. Integrative regulatory mapping indicates that RNA-binding protein HuR couples pre-mRNA splicing and mRNA stability. (In Revision).
Neplioueva V, Dobrikova EY, Mukherjee N, Keene JD, Gromeier M. Tissue type-specific expression of the dsRNA-binding protein 76 and genome-wide elucidation of its target mRNAs. PLoS ONE (2010) vol. 5 (7) pp. e11710
Morris AR, Mukherjee N, Keene JD. Wiley Interdiscip Rev Syst Biol Med (2010) vol. 2 (2) pp. 162-80
Mukherjee N, Lager PJ, Friedersdorf MB, Thompson MA, Keene JD. Coordinated posttranscriptional mRNA population dynamics during T-cell activation. Mol Syst Biol. 2009;5:288. Epub 2009 Jul 28.
Papadaki O, Milatos S, Grammenoudi S, Mukherjee N, Keene JD, Kontoyiannis DL. Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR. J Immunol. 2009 Jun 1;182(11):6779-88.
Morris AR, Mukherjee N, Keene JD. Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets. Mol Cell Biol. 2008 Jun;28(12):4093-103. Epub 2008 Apr 14.
Gottwein E, Mukherjee N, Sachse C, Frenzel C, Majoros WH, Chi JT, Braich R, Manoharan M, Soutschek J, Ohler U, Cullen BR. A viral microRNA functions as an orthologue of cellular miR-155. Nature. 2007 Dec 13;450(7172):1096-9.
Zhai GG, Malhotra R, Delaney M, Latham D, Nestler U, Zhang M, Mukherjee N, Song Q, Robe P, Chakravarti A. Radiation enhances the invasive potential of primary glioblastoma cells via activation of the Rho signaling pathway. J Neurooncol. 2006 Feb; 76(3):227-37.
Zhang M, Mukherjee N, Bermudez RS, Latham DE, Delaney MA, Zietman AL, Shipley WU, Chakravarti A. Adenovirus-mediated inhibition of survivin expression sensitizes human prostate cancer cells to paclitaxel in vitro and in vivo. Prostate. 2005 Aug 1; 64(3):293-302.
Tennis, Soccer, Hiking