Duke University Medical Center
       
Research
   
 
the Sullivan Lab
  • Balakumaran BS, Porrello A, Hsu DS, Glover W, Foye A, Leung JY, Sullivan BA, Hahn WC, Loda M, Febbo PG. (2009) MYC Activity Mitigates Response to Rapamycin in Prostate Cancer through Eukaryotic Initiation Factor 4E-Binding Protein 1-Mediated Inhibition of Autophagy. Cancer Res 69(19):7803-10. pdf

  • Mravinac B, Sullivan LL, Reeves JW, Yan CM, Kopf KS, Farr CJ, Schueler MG, Sullivan BA. (2009) Histone Modifications within the Human X Centromere Region. PLoS ONE 4(8): e6602. doi:10.1371/journal.pone.0006602. pdf

  • Gopalakrishnan S, Sullivan BA, Trazzi S, Della Valle G, Robertson KD. (2009) DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions. Human Mol Genet 18: 3178–3193 doi:10.1093/hmg/ddp256. pdf

  • Kim JH, Ebersole T, Kouprina N, Noskov VN, Ohzeki J, Masumoto H, Mravinac B, Sullivan BA, Pavlicek A, Dovat S, Pack SD, Kwon YW, Flanagan PT, Loukinov D, Lobanenkov V, Larionov V. (2009) Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing. Genome Res 19(4):533-44. pdf

  • Gao F, Ponte JF, Levy M, Papageorgis P, Cook NM, Ozturk S, Lambert AW, Thiagalingam A, Abdolmaleky HM, Sullivan BA, Thiagalingam S. (2009) hBub1 negatively regulates p53 mediated early cell death upon mitotic checkpoint activation. Cancer Biol Ther 8(7):55-63.

  • Dai J, Sullivan BA, and Higgins JM. (2006) Regulation of mitotic chromosome cohesion by haspin and aurora B, Dev Cell 11:741-750 (BAS-cover illustration). pdf

  • Schueler MG, Sullivan BA. (2006) Structural and functional dynamics of human centromeric chromatin. Annu Rev Genomics Hum Genet 7:301-13.

  • Lam AL, Boivin CD, Bonney CF, Rudd MK, Sullivan BA. (2006) Human centromeric chromatin is a dynamic chromosomal domain that can spread over non-centromeric DNA. Proc Natl Acad Sci USA 103:4186-4191. pdf

  • Scott KC, Sullivan BA. (2005) Epigenetic Inheritance and RNAi at the centromere and heterochromatin. In Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics, (Section editor: R. Nicholls), Edited by Lynn Jorde (John Wiley & Sons), doi: 10.1002/04701153X.g103322.

  • Wilson KC, Cattel DJ, Wan Z, Rahangdale S, Ren F, Kornfeld H, Sullivan BA, Cruikshank WW, Center DM. (2005) Regulation of prointerleukin-16 and p27Kip1 in primary human T lymphocytes, Cell Immunol 237:17-27.

  • Lam AL, Pazin DE, Sullivan BA. (2005) Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions. Chromosoma 114:242-51. pdf

  • Sullivan, BA. (2004) Centromeres. In Encyclopedia of Biological Chemistry. (W.J. Lennarz and M.D. Lane eds), Elsevier, Oxford, Vol.1, pp. 367-371.

  • Sullivan BA, Karpen GH. (2004) Centromeric chromatin displays a histone modification pattern that is distinct from both euchromatin and heterochromatin. Nat Struc Mol Biol 11:1076-1083 (+ cover illustration). pdf

  • Sullivan, BA. (2002) Centromere round-up at the heterochromatin corral. Trends Biotech 20:89-92. pdf

  • Blower MD*, Sullivan BA*, Karpen GH. (2002) Conserved organization of centromeric chromatin in flies and humans. Dev Cell 2:319-330 (*joint first authors; BAS-cover illustration). pdf

  • Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH. (2002) Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. Genome Biol 3:85.1-85.16.
  • Sullivan BA, Blower MD, Karpen GH. (2001) Determining Centromere Identity: Cyclical Stories And Forking Paths. Nat Rev Genet 2:584-596. pdf

  • Sullivan BA, Karpen GH. (2001) Centromere identity in Drosophila is not determined in vivo by replication timing. J Cell Biol 154:683-690. pdf
  • Gong Y, RB Slee et al. (2001) LDL Receptor-Related Protein 5 (LRP5) affects bone accrual and eye development. Cell 107:513–523.

  • Sullivan BA, Bickmore WA. (2000) Unusual chromosome architecture and behaviour at an HSR. Chromosoma 109:173-180. pdf

  • Sullivan BA & PE Warburton (1999) Studying the progression of vertebrate chromosomes through mitosis by immunofluorescence and FISH. In Chromosome Structural Analysis: A Practical Approach, p 81-101, Edited by Dr. Wendy Bickmore (IRL Press).

  • Sullivan BA & HF Willard (1998) Stable dicentric X chromosomes with two functional centromeres. Nat Genet 20:227-228. pdf

  • Flejter, WL, B Issa, BA Sullivan, JC Carey, & AR Brothman (1997) Variegated aneuploidy in two siblings with microcephaly, growth deficiency, and minor somatic anomalies. Amer J Med Genet 75:45-51.

  • Depinet TW, JL Zackowski, WC Earnshaw, S Kaffe, GS Sekhon, R Stallard, BA Sullivan, GH Vance, DL Van Dyke, HF Willard, AB Zinn, & S Schwartz (1997) Characterization of neo-centromeres in marker chromosomes lacking detectable alpha-satellite DNA. Hum Mol Genet 6:1195-1204.

  • Warburton PE, CA Cooke, S Bourassa, O Vafa, BA Sullivan, G Stetten, G Gimelli, D Warburton, C Tyler-Smith, KF Sullivan, GG Poirier, & WC Earnshaw (1997) Immunolocalization of CENP-A, a kinetochore-specific histone H3 variant, suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Curr Biol 7:901-904. pdf

  • Sullivan BA, S Schwartz, & HF Willard (1996) Centromeres of human chromosomes. Environ Mol Mutagenesis 28:182-191.

  • Sullivan BA, LJ Jenkins, J Leana-Cox, E Karson, & S Schwartz (1996) Evidence for structural heterogeneity from molecular cytogenetic analysis of dicentric Robertsonian translocations. Amer J Hum Genet 59:167-175. pdf

  • Sullivan BA, CA Schiffer, SR Patil, D Hulseberg, J Leana-Cox, & S Schwartz (1995) Application of FISH to rearrangements associated with chronic myelogenous leukemia. Cancer Genet Cytogenet 82:93-99.

  • Sullivan BA & S Schwartz (1995) Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are essential components of functional centromeres. Hum Mol Genet 4:2189-2198 (+ cover illustration). pdf

  • Sullivan BA, DJ Wolff, and S Schwartz (1994) Analysis of centromeric activity in dicentric Robertsonian translocations: Implications for a functional acrocentric hierarchy. Chromosoma 103:459-467. pdf

  • Leana-Cox J, S Levin, R Surana, E Wulfsberg, CL Keene, LJ Raffel, B Sullivan, and S Schwartz (1993) Characterization of de novo duplications in eight patients by using fluorescence in situ hybridization with chromosome-specific DNA libraries. Amer J Hum Genet 52:1067-1073. pdf

  • Sullivan BA, Leana-Cox J, and S Schwartz (1993) Clarification of subtle reciprocal rearrangements using fluorescence in situ hybridization. Amer J Med Genet 47:223-230.

Cell Cover
cover art 2006






Nature Cover
cover art 2004





Developmental Cell Cover
cover art 2002




 


Human Molecular Genetics Cover
cover art 1995

 

Department of Molecular Genetics & Microbiology Institute for Genome Sciences & Policy
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copyright 2007 Page updated 10.20.2009